【 中文摘要 】本發明公開了白桦脂醛在制備用于預防或治療神經退行性疾病的藥物中的應用，涉及生物醫學技術領域。本發明發現，白桦脂醛通過提高TFEB介導的自噬功能，以清除PD和AD的病理分子標志物α‑syn和p‑Tau，有望成爲防治PD和/或AD的潛在藥物，爲相關疾病的新藥開發和病理機制的研究開發提供了新的途徑和基礎。

【 英文摘要 】The invention discloses an application of betulin in preparation of a medicament for preventing or treating neurodegenerative diseases, and relates to the technical field of biomedicine. According to the invention, betulinic aldehyde is found to remove pathological molecular markers alpha-syn and p-Tau of PD and AD by improving TFEB-mediated autophagy function, so that the betulinic aldehyde is expected to become a potential drug for preventing and treating PD and/or AD, and provides a new approach and foundation for the development of new drugs for related diseases and the research and development of pathological mechanisms.

[ 英文標題 ]

【 技術功效 】

【技術分類】

【行業分類】

【 首項權利要求-原文 】

1.白桦脂醛在制備用于預防或治療由自噬溶酶體途徑異常導緻的相關疾病的藥物中的應用。

【 首項權利要求-翻譯 】

1. The application of the betulinic aldehyde in preparing the medicine for preventing or curing the relative disease caused by the autophagy lysosomal route abnormity.